They are usually benign (non-cancerous), but in some cases can be locally aggressive and have the potential to recur.
They are characterised by the presence of a large number of multinucleated giant cells as well as stromal cells. They most commonly occur in the long bones, such as the distal femur (thigh bone) and the proximal tibia (shin bone), but can also occur in other bones.
Symptoms may include pain, swelling and a limited range of motion in the affected area. Treatment options may include surgery to remove the tumour, curettage (scraping out the tumour), and bone grafting. In some cases, additional treatments such as radiation therapy or targeted therapy may be used, especially if the tumour is aggressive or has a high risk of recurrence.