SHINING A LIGHT ON SARCOMA

Gastrointestinal Stromal Tumours (GIST)

Gastrointestinal stromal tumours (GISTs) develop in the gastrointestinal (GI) tract, which includes the stomach, small intestine and oesophagus.

About Gastrointestinal Stromal Tumours (GIST)

They arise from specialised cells called the interstitial cells of Cajal, which help regulate the movement of food through the digestive system.

GISTs can occur at any age but are more commonly diagnosed in adults. The exact cause is unknown, but most cases are associated with certain genetic mutations, particularly in the KIT or PDGFRA genes.

Gastrointestinal Stromal Tumours (GIST) Subtypes

No subtypes found.

Last reviewed 10/04/2026